Toxicology Project Leader (Investigative Toxicology)

Our client, a leading Biotech focusing on the discovery and development of novel biologics, are seeking to hire a Toxicology Project Leader.

The primary role and responsibility is to ensure compliance with GLP, SOPs and study protocols in conducting toxicology studies, and to ensure compliance with regulatory requirements and company policies to enable projects to advance.

You will be accountable for the definition of toxicology-related stage-gating criteria and pre-clinical milestones to inform decision-making across all NCE and NBE research.

Job Responsibilities:

• Develop in-depth understanding and strategy for management of target and asset-specific liabilities.
• Develop and implement toxicology strategy for lead optimization and candidate selection.
• Identify collaborative opportunities in toxicology science consistent with the strategic focus of internal discovery therapeutics.
• Design and implement nonclinical investigative toxicology studies.
• Conduct studies and participate in activities related to the Investigational New Drug (IND) application and other regulatory approvals.

Skills and Requirements:

• PhD or DVM with post-doctoral experience and publication track record in toxicology disciplines, preferably in immuno- or molecular toxicology
• Work experience, after postdoc, in investigative toxicology or related fields (immunology, pathology, cell biology) demonstrating sustained record of achievement and ability to understand translational pathobiology
• Board certification in toxicology and experience in interacting with regulatory agencies
• Background in applied sciences and clinical-stage application of safety biomarkers
• Broad technical expertise and experience with in vitro and in vivo models to address safety issues
• Understand cutting-edge sciences and technology applied to enhance investigations of drug candidate safety liabilities
• Ability to work both independently and cross-functionally
• Excellent communication and presentation skills

To Apply:

Please click on the Apply button. Please include a short note outlining why you are interested in the role and why you think you are suitable.
In case you have difficulty in applying or if you have any questions, please call Chidozie Orji on +44 207 4400 671 or upload your CV on our website - www.Proclinical.com.
A full job description is available on request.
Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

#LI-CO1