Associate Principal Scientist, Lipid Chemistry & Drug Delivery

Proclinical is currently seeking an Associate Principal Scientist, Lipid Chemistry & Drug Delivery to join an innovative biopharma company in Boston supporting various therapeutic programs including small molecules, peptides, oligonucleotides and RNA-based therapeutics. We are looking for a highly motivated chemist with a strong foundation in the lipid chemistry and delivery sciences to support new modality projects.

Job Responsibilities:

• Designing, synthesizing, purifying and analyzing novel lipids for lipid nano-particle based delivery platform with minimum supervision; Generating, evaluating and reporting data clearly and reliably.
• Acting as the key delivery chemist/formulation subject matter expert in project teams for the delivery of nucleic acid therapeutics; Providing data interpretation and making recommendations to project leaders and other stakeholders.
• Presenting data at internal meetings and occasionally at external meetings.
• Leading cross-site, cross-functional projects and workstreams.

Skills and Requirements:

• PhD degree in Polymer Chemistry, Organic Chemistry, Medicinal Chemistry, Pharmaceutical Sciences or related scientific disciplines with 5-10 years post-graduation experience in a pharmaceutical and/or biotechnology environment.
• Demonstrated ability in designing and optimizing synthetic strategies and approaches of lipids and/or polymers
• Proficiency with analytical and physicochemical characterization of novel materials (e.g. NMR, LC/MS, particle sizer, various separation technologies)
• Solid understanding of novel delivery technologies including but not limited to microspheres, lipid based formulation, nanoparticles
• Track record of scientific excellence in terms of scientific publications, patents, and/or conference presentations
• Excellent oral and written communication skills
• Knowledge of pharmaceutical new modalities (e.g. oligonucleotides, RNA, DNA, peptides, proteins)
• Experience with new modalities (e.g. oligonucleotides, RNA, DNA, peptides, proteins)
• Experience with outsourcing
• Experience with formulation and pharmaceutical sciences
• Experience with bio-conjugation

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 857-362-9542 or M.Robinson@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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