Senior USP Scientist

Proclinical is seeking a dedicated Senior Scientist for a hybrid role. This position focuses on the development and optimization of scalable upstream manufacturing processes, particularly involving bioreactors and viral vectors. The successful candidate will have to have a proactive approach to scientific experimentation and collaboration with internal and external teams.

Responsibilities:

• Independently and collaboratively set up and handle bioreactors for manufacturing research/nonclinical grade viral vectors and recombinant proteins using mammalian cell suspension systems.
• Develop and optimize scalable upstream manufacturing processes using tools like Design of Experiments (DoE).
• Lead the development and implementation of methods and protocols.
• Execute, analyze, quality control, and present data within the scope of work.
• Design, execute, and document scientific experiments with high quality and timeliness.
• Provide project summaries and reports, adhering to established quality standards and accurate record-keeping.
• Ensure knowledge transfer and training of junior staff and colleagues.
• Collaborate with the internal CMC team for the transfer of manufacturing and quality aspects from Research to CMC.
• Support work involving external collaborations and Contract Development & Manufacturing Organizations (CDMOs).
• Source, develop, and evaluate technologies and processes for AAV batches to improve yield, quality, and impurity profiles.

Key Skills and Requirements:

• D. in a relevant discipline or equivalent industry experience.
• Experience in running bioreactors with suspension cultures of mammalian cells.
• Experience in viral vector (especially AAV) manufacture in bioreactors and conducting Design of Experiment (DoE) studies.
• Familiarity with biochemical analytical monitoring of bioreactors.
• Strong communication skills and ability to work effectively as part of a team.
• Evidence of scientific accomplishments through publications and presentations.
• Strong critical, scientific, and strategic thinking skills.
• Experience in interpreting and presenting data to stakeholders.

If you are having difficulty in applying or if you have any questions, please contact Ruhee Saleh at r.saleh@proclinical.com

Apply Now:

If you are interested in learning more or applying to this exciting opportunity, please complete the form below and attach a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist, please request a call back at the top of this page.

Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy.