Research Scientist, Purification Process Science job in Wilmington, USA

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First Name*

Last Name*

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Job type: Permanent

Discipline: Analytical Chemistry, Biochemistry, Molecular Biology

Location: United States

This vacancy has now expired

Proclinical is currently recruiting for a Research Scientist of Purification Process Science for a pharmaceutical company located in Wilmington, DE. Successful candidate will support protein purification process development and optimization primarily for novel therapeutic monoclonal antibody products including bispecifics throughout all stages of clinical trials.

Job Responsibilities:

Conduct routine protein purification to support discovery team's material needs and cell culture development
Conduct high-throughput protein purification to support cell line development
Conduct purification process development, optimization, and pilot scale-up manufacturing
Conduct routine analyses of in-process samples using relevant product purity and process impurity analytical tools
Prepare buffers and solutions needed for laboratory work
Manage laboratory supplies and instrument maintenance
Write routine electronic laboratory notebook and development reports
Participate and present updates in routine group meetings
Other responsibilities as assigned

Skills and Requirements:

BS or MS. degree in biochemistry, bioengineering, biology, chemistry or related fields with a minimum of 2 years of relevant industry experiences
Good knowledge in protein chemistry and bioprocessing
Good knowledge and hands-on experiences in various types of column/membrane chromatography (affinity, size exclusion, ion exchanges, HIC, multi-mode) and filtration technology (TFF and nanofiltration) for cell culture clarification, protein purification and analysis
Experiences in protein purification process development and scale-up
Experiences in using AKTA line of purification instruments from lab scale to pilot scale
Experiences in using UF/DF instrument for buffer exchange, product concentration, and formulation
Experiences in using depth filtration for cell culture clarification
Experiences in using analytical instruments for protein analysis such as HPLC, SoloVPE, SDS-PAGE or SDS-CGE, ELISA, etc.
Good verbal and written communication skills
Organized, cooperative, independent, meticulous
Experiences in Design Of Experiment approach and high-throughput protein purification platform will be a plus

To Apply:

Please click on the Apply button. Please include a short note outlining why you are interested in the role and why you think you are suitable.

In case you have difficulty in applying or if you have any questions, please call Matt Tong at (+1) 646-878-6308 or upload your resume on our website - www.proclinical.com.

A full job description is available on request.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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