Scientist/ Senior Scientist, AAV Bioanalytical Assay Dvlopment

Proclinical is seeking a Principal/Senior Research Associate Bioanalytical Assay Development for a leading gene therapy company located in Boston, MA. The successful candidate will be responsible for the development of bioanalytical methods to support AAV-based gene therapy programs. S/he will be required to design and execute various bioanalytical assays (method development, qualification, method transfer, internal or external assay validation support).

Job Responsibilities:

• Independently design, develop, troubleshoot, qualify and implement various bioanalytical assays and provide various bioanalytical assay support for all gene therapy programs.
• Conduct routine sample testing to support gene therapy research and development
• Participate in departmental and cross functional project teams
• Author study reports, SOPs, and assay procedures
• Maintain detailed and well-organized documentation with best industry practice
• Effectively analyze, summarize and present the data to the project teams
• Collaborate with internal cross-functional team members and external CROs

Skills and Requirements:

• Ph.D. in Cell and/or Molecular Biology, Biochemistry, Pharmacology, Immunology or related disciplines, with 5+ years of postdoctoral laboratory or industry experience working in a neuroscience, immunology, AAV gene therapy, or bioanalytical laboratory.
• Extensive technical and hands-on experience in development, optimization, qualification, validation and method transfer of various bioanalytical assays in different biological matrices (rodent, NHP, human, etc.) for non-GLP/GLP studies
• In-depth knowledge and hands-on experience in cell culture and cell-based assays, cell and tissue processing, ELISA, western blot, RT-qPCR, bDNA assay, ddPCR, LC-MS/MS, MSD, SIOMA and other various platforms
• Ability to learn new techniques and perform multiple tasks simultaneously
• Proven ability to work independently and to be a good team player in a hands-on laboratory setting
• Self-motivated, have pro-active and positive can-do attitude
• Strong scientific, computer, organizational, and documentation skills, attention to detail
• Strong analytical and problem-solving skills
• Being willing to work in a fast-paced start-up environment with demonstrated capacity to handle multiple tasks and demands
• Experience in AAV gene therapy is a plus

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 857-362-9542 or m.robinson@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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