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Job type: Permanent

Discipline: Biological Sciences, Bioprocessing, Pharmacology

Location: United States

Proclinical is currently recruiting for a Senior Scientist - Immunology with a pharmaceutical company located in Cambridge, MA.

Job Responsibilities:

Work in partnership with cross-functional project teams to investigate the biology of novel targets and to evaluate the effects of newly developed drug lead candidates on immune cell function
Design and conduct human and rodent cell- and tissue-based immunoassays for target identification and validation
Perform hands-on experimentation using a wide range of molecular and cellular techniques suitable for drug target identification and validation
Generate, analyze, interpret, present experimental results at various meetings to partners/collaborators and collaboratively plan experimental paths forward
Generate study reports and maintain a detailed record of experiments in electronic lab notebooks in accordance with company policy
Share in responsibilities to support general lab functions

Skills and Requirements:

PhD in the fields of Cell biology, Immunology or related fields with a track record of publications.
Strong background in immunology or related fields
Excellent written and oral communication skills
Able to work independently and as part of a dynamic team in a multidisciplinary matrix environment
Team spirit and excellent interpersonal skills
Learning agility and drive to continuously improve and develop
Self-motivated and meticulous, with focus on critical and innovative thinking
Isolation and sterile tissue culture of mammalian cell lines and immune cell subsets
Cell-based assay development using primary rodent and human immune cells and immortalized cell lines
Multicolor FACS (flow cytometry set-up, acquisition, analysis and reporting)
Multiplex protein detection (ELISA, Luminex, MSD)
Gene expression analysis (NanoString, NGS, scRNA-Seq)
Molecular biology (transfection, transduction, stable cell line generation, Western Blot)
Previous drug discovery experience in a biopharmaceutical setting
Hands-on experience utilizing functional genomics approaches (CRISPR-Cas, si/hRNA) for phenotypic screening and target ID/validation in cell lines or primary immune cells

If you are having difficulty in applying or if you have any questions, please contact Sarah Beshara at 267-477-3355.

ProClinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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