Scientist

A Research and Development team in Belgium are looking for a talented Scientists for a temporary position to deliver on objectives, foster an environment of collaboration and positive communication.

Job Responsibilities

• Support protein production from small-scale expression testing to upscaling and protein purification and quality control analysis of produced proteins for H2L and LO activities in the different TA projects
• Majority of time will be hands-on work in the laboratory
• Perform protein expression in bacteria, yeast, baculovirus / insect cells and mammalian systems to support the purification of proteins for screening, crystallography and assay development.
• Test innovative approaches to protein production including evaluation of new technologies
• Perform quality control on produced proteins
• Analyse, interpret, summarise and report experimental data. Maintain accurate records (electronic notebook). Write and update protocols and reports.
• Present results and conclusions at internal team meetings.
• Assist or take responsibility for various tasks such as shipping logistics, database entry of externally produced reagents, maintenance of cell lines, etc.
• Review reports for accuracy and completeness.
• Communicate effectively with investigational staff, team members and functional manager.
• Work under limited supervision with a high level of autonomy
• Strictly adhere to local safety regulations and laboratory rules

Skills and Requirements

• B.S./B.A in Biology, Biochemistry or equivalent with 5-10 years of industry work experience is required. Master's degree with 2 or more years industry experience
• Experience in recombinant expression of proteins in various heterologous systems (E. coli bacteria, insect cells, mammalian cell lines, cell-free systems) is required
• Expertise in the purification of high-quality proteins using standard techniques and equipment is required
• Expertise in protein characterisation using techniques such as analytical gel filtration, mass spectrometry, dynamic light scattering, nano DSF, SPR is preferred
• Experience in protein construct design is preferred
• Knowledge of protein crystallisation and structure determination is a plus

To Apply

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