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Job type: Permanent

Discipline: Biological Sciences

Location: Belgium

A Research and Development team in Belgium are looking for a talented Scientists for a temporary position to deliver on objectives, foster an environment of collaboration and positive communication.

Job Responsibilities

Support protein production from small-scale expression testing to upscaling and protein purification and quality control analysis of produced proteins for H2L and LO activities in the different TA projects
Majority of time will be hands-on work in the laboratory
Perform protein expression in bacteria, yeast, baculovirus / insect cells and mammalian systems to support the purification of proteins for screening, crystallography and assay development.
Test innovative approaches to protein production including evaluation of new technologies
Perform quality control on produced proteins
Analyse, interpret, summarise and report experimental data. Maintain accurate records (electronic notebook). Write and update protocols and reports.
Present results and conclusions at internal team meetings.
Assist or take responsibility for various tasks such as shipping logistics, database entry of externally produced reagents, maintenance of cell lines, etc.
Review reports for accuracy and completeness.
Communicate effectively with investigational staff, team members and functional manager.
Work under limited supervision with a high level of autonomy
Strictly adhere to local safety regulations and laboratory rules

Skills and Requirements

B.S./B.A in Biology, Biochemistry or equivalent with 5-10 years of industry work experience is required. Master's degree with 2 or more years industry experience
Experience in recombinant expression of proteins in various heterologous systems (E. coli bacteria, insect cells, mammalian cell lines, cell-free systems) is required
Expertise in the purification of high-quality proteins using standard techniques and equipment is required
Expertise in protein characterisation using techniques such as analytical gel filtration, mass spectrometry, dynamic light scattering, nano DSF, SPR is preferred
Experience in protein construct design is preferred
Knowledge of protein crystallisation and structure determination is a plus

To Apply

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