Histotechnologist

US$80000 - US$100000 per annum
  1. Permanent
  2. Biological Sciences
  3. United States
San Francisco, USA
Posting date: 17 Sep 2026
70149

Histotechnologist - Permanent - Newark, CA

Passionate about transforming tissue into breakthrough insights? Step into a role where your histology expertise drives real drug discovery impact.

We are seeking a Histotechnologist to join our client's dynamic team in CA, US.

Primary Responsibilities:

The successful candidate will support research projects by performing histological procedures, including tissue preparation, sectioning, standard staining, immunostaining, imaging, and image quantification.

Skills & Requirements:

  • BS or MS in Biology, Biomedical Sciences, Histology, Pathology, Cell Biology, Molecular Biology, or a related scientific discipline.
  • Approximately 3+ years of relevant histology experience in biotechnology, pharmaceutical, CRO, academic research, or a related laboratory environment.
  • Demonstrated hands-on experience with FFPE and fresh-frozen tissue workflows.
  • Strong experience with tissue processing, embedding, microtomy and/or cryosectioning, and histological staining.
  • Experience performing H&E and immunohistochemical staining.
  • Experience using microscopy to assess tissue morphology and staining quality.
  • Experience operating and performing routine maintenance on histology laboratory equipment.
  • ASCP certification (HT or HTL) is desirable
  • Experience in performing, optimizing, and implementing qualitative and quantitative tissue-based methodologies, ranging from tissue handling and processing, sectioning with microtome or cryostat, and histochemical staining, is required
  • Experience developing, optimizing, or troubleshooting IHC, IF, ISH, or other tissue-based assays.
  • Experience with automated immunostaining platforms such as Leica Bond RX, Biocare IntelliPATH, or comparable systems.

The Histotechnologist's responsibilities will be:

  • Preparation of tissue, including grossing and embedding
  • Sectioning tissue using various equipment, including cryostat, microtome, vibratome, and sliding-frozen microtome
  • High-volume automated immunostaining
    • Experience with chromogenic and fluorescence immunodetection (single and multiplex)
    • Experience with automatic slide stainers such as Leica Bond Rx and Biocare IntelliPATH FLX is a plus
  • Perform end-to-end histology workflows including tissue fixation, grossing, processing, embedding, sectioning, staining, imaging, and slide preparation.
  • Work with both FFPE and fresh/frozen tissue samples across a variety of tissue types.
  • Perform tissue sectioning using microtomes and cryostats; experience with additional sectioning platforms such as vibratomes or sliding microtomes is beneficial.
  • Perform routine histological staining including H&E, nuclear counterstaining, and other special stains.
  • Execute and support IHC, IF, and/or ISH assays, including both manual and automated staining workflows.
  • Support single- and multiplex immunodetection using chromogenic and/or fluorescence-based methods

Compensation:

  • $80 000 - $100 000 Per Annum

If you are having difficulty in applying or if you have any questions, please contact Shannon Briggs at s.briggs@proclinical.com.

If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.

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