Upstream Manufacturing Manager

Highly Competitive Salary
  1. Permanent
  2. Manufacturing, Project Engineering, Operations Management
  3. United States
Raleigh, USA
Posting date: 28 Aug 2020

Proclinical is currently recruiting for an Upstream Manufacturing Manager with a global Biopharmaceutical company located in Raleigh, NC. As the Upstream Manufacturing Manager, you will play a key role in leading a production team and managing resources in order to maximize production and ensure quality and safety standards.

Job Responsibilities:

  • Accountable and responsible for leading production teams to achieve targets and deliver and improve process or product consistency, quality/compliance, cost standards, etc.
  • Ensure that work performed by teams are accurate, timely, efficient and compliant with corporate policies, plant SOPs, cGMP regulations, and FDA regulations.
  • Participate in investigations and continuous improvement initiatives.
  • Apply LEAN manufacturing and Six Sigma to improve quality, cost, safety and/or cycle time.
  • Effectively collaborate with cross functional teams to ensure production goals are met and investigations are accurate and complete.
  • Coordinate, schedule, and participate in daily activities of cGMP production in the manufacturing area to meet supply chain needs.
  • Ensure that product quality is maintained through all phases of process validation and commercial production.
  • Review completed batch records, develop training material, update curricula, close training gaps, and support the training of new supervisors.

Skills and Requirements:

  • BS degree with 5 years GMP manufacturing experience required or MS degree with 3 years; experience.
  • Hands-on experience with adherent and/or suspension cells
  • Experience in upstream process and equipment troubleshooting.

If you are having difficulty in applying or if you have any questions, please contact Alex Tooulas at (+1) 917-284-9670 or

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.