Research Investigator

Proclinical is currently recruiting for a Research Investigator, Antibody Pharmacology with a pharmaceutical company located in Wilmington, DE. The successful candidate is able to work independently and demonstrates a broad understanding of immunology and cancer biology, being able to use this knowledge to design and execute a research plan that answers critical questions about compounds and targets under evaluation.

Job Responsibilities:

• Design, execute, and interpret cell-based in vitro experiments to explore the therapeutic potential of antibodies
• Develop new assays to screen functional activity of antibodies
• Culture of cell lines and isolation and culture of human PBMCs
• Design appropriate in vivo models to answer key biological and pharmacological questions
• Establish and conduct in vivo pharmacodynamics studies
• Evaluate data, prepare reports and presentations for internal and external meetings
• Work collaboratively across multiple functional groups within drug discovery and clinical development to achieve key goals

Skills and Requirements:

• D. in Immunology, Cancer Biology, Pharmacology or related field
• Preferred post-doctoral experience in a relevant field
• Strong background in immunology, antibody-related functions, and oncogenic signaling pathways
• Minimum of 2 years of pharmaceutical or biotech experience
• Mouse work experience including in vivo models of cancer
• Expertise in the following techniques is mandatory: magnetic cell isolation, cell culture, tumor implantation, isolation, and dissection (mouse models), immune cell phenotyping, multicolor flow cytometry (BD cytometers), ELISA, MSD, Western blot for phospho-proteins, MLR, ADCC, basic molecular biology including isolation of nucleic acid and real-time PCR
• Excellent communication skills

If you are having difficulty in applying or if you have any questions, please contact Dominic Santoro at 215-531-5280.

ProClinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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