Research Associate, NGS job in Cambridge, USA

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First Name*

Last Name*

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Job type: Permanent

Discipline: Biological Sciences, Genetics & Genomics, Molecular Biology

Location: United States

This vacancy has now expired. Please see similar roles below...

Proclinical is currently recruiting for a Research Associate with a clinical stage biotechnology company located in Cambridge, MA. As the Research Associate, you will be working for a fast-growing, innovative biotechnology company developing the next generation of personalized cancer immunotherapies. The company brings together distinguished scientific founders, an experienced and diverse management team, a seasoned and successful board of directors, and very deep financial backing to tackle fundamental challenges at the intersection of cancer biology, immunology and immunotherapy design.

Job Responsibilities:

Responsible for the execution of established histology, and next-generation sequencing assays in the GMP Next Generation Sequencing (NGS) laboratory.
Develop breakthrough immunotherapy treatments for patients with cancer.
Identify and deploy neoantigens from each patient's tumor to develop personalized cancer vaccines.
Responsible for the GMP compliant processing of cancer patient samples through nucleic acid extraction and next generation sequencing.
Maintain batch record reports, consumable inventory, equipment maintenance and calibration to maintain quality control and compliance.

Skills and Requirements:

Bachelor's degree (or equivalent) in scientific discipline or a health-related field.
1+ years relevant experience, including in a regulated setting (title can be adjusted based on level of experience).
Strong background in molecular biology and associated general laboratory techniques (PCR, qPCR, nucleic acid purification).
Histology experience (microtome operation and FFPE sectioning).
Familiarity with NGS workflows including nucleic acid extraction from various tissue specimens (cell line, blood, fresh frozen and FFPE), Illumina-based library construction, and hybrid capture enrichment.
Operation and maintenance of instrumentation critical for Illumina NGS workflows (qPCR, plate readers and HiSeq/MiSeq/NovaSeq sequencers).
CLIA/CAP or cGMP experience.
Experience working with automated liquid handling.
Experience with LIMS.
Experience working with Quality Assurance and Quality Control teams.
Impeccable documentation practices and attention to detail.
Maintaining cleanliness and orderliness of operational area.
The ability to prioritize and complete tasks in a timely manner.
Excellent written and verbal communication skills.
A willingness to work hard in a fast-paced environment.

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 617-903-7746 or m.robinson@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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