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Job type: Permanent

Discipline: Analytical Chemistry

Location: United Kingdom

Proclinical are recruiting for a Lead Scientist ASMS - Affinity Selection Mass Spectrometry to join a CRO. This role is on a permanent basis and is located in Nottingham.

Responsibilities:

Guide establishment of ASMS technology within the business.
Be included in business-connected actions, for example: quote generation, BD/marketing material, promoting Company capabilities at conferences, meetings etc.
You will develop and preserve consciousness of, and partake in, project method, etc.
Recognise and drive new prospects in ASMS utilisation and ability to develop, which involves reviewing innovative techniques and tools.
The ideal candidate will design and implement personal experiments independently to quality, running work streams in parallel as suitable in a timely manner.
Other duties may be assigned to this role.

Key Skills and Requirements:

Educated to an advanced degree level in an analytical chemistry or similar field.
Familiarity with mass spectrometry-based, screening small molecule libraries in biotech or pharmaceutical industrial settings.
Knowledge in the design, development, validation, and implementation of ASMS/MS characterisation of ligand-target interactions and quantitative data analysis.
Acquaintance with ASMS technology.
Capable of implementing liquid chromatography-mass spectrometry for recognition of innovative ligand-target interactions pertinent to small molecule drug discovery campaigns.
Able to utilise multiple assay platforms along with MS-based small molecule affinity screens.
Prior involvement with both two-dimensional liquid chromatography and size exclusion chromatography.
A background in implementing scientific strategy to resolve issues and troubleshoot LC and MS technical problems.
Comprehension of the principles for hit recognition and validation.
Comprehension of data analysis principles as applied to large data sets and acquaintance with data analysis software packages with particular focus on small molecule MS analysis.
Abilities in data organisation and downstream reporting of MS data to other disciplines such as medicinal chemistry, pharmacology, etc.
Presentation and communication skills both verbally and inwriting.
Works well with others in a team.

If you are having difficulty in applying or if you have any questions, please contact James Hume at +44 208 167 5468.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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