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Job type: Contract

Discipline: Analytical Chemistry, Biochemistry, Medicinal Chemistry

Location: United States

Proclinical is seeking an Associate Scientist of Process Chemistry for a leading pharmaceutical company located in Cambridge, MA. The successful candidate will be a part of the Process Chemistry group, responsible for the process development and in-house non-GMP manufacture of modified oligonucleotides and siRNAs.

Must be eligible to work in the US.

Job Responsibilities:

Support non-GMP oligonucleotide production on a tight timeline
Support purification method development, optimization, and scale-up
Execute non-GMP oligonucleotide purifications
Execute downstream processing of purified material
Execute in-process analytical tests
Participate in creating and reviewing SOPs and batch records
Support campaign activities across other unit operations as-needed

Skills and Requirements:

BS in Chemistry with 1-3 years lab experience, preferably in an industrial setting.
Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
Experience in record-keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
Good communication skill is a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.

If you are having difficulty in applying or if you have any questions, please contact Jackie Cerchio at +(1) 267-846-2026 or j.cerchio@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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