Associate Scientist - Process Chemistry

Highly Competitive Salary
  1. Contract
  2. Analytical Chemistry, Biochemistry, Medicinal Chemistry
  3. United States
Cambridge, USA
Posting date: 11 Aug 2023

This vacancy has now expired. Please see similar roles below...

Proclinical is seeking an Associate Scientist of Process Chemistry for a leading pharmaceutical company located in Cambridge, MA. The successful candidate will be a part of the Process Chemistry group, responsible for the process development and in-house non-GMP manufacture of modified oligonucleotides and siRNAs.

Must be eligible to work in the US.

Job Responsibilities:

  • Support non-GMP oligonucleotide production on a tight timeline
  • Support purification method development, optimization, and scale-up
  • Execute non-GMP oligonucleotide purifications
  • Execute downstream processing of purified material
  • Execute in-process analytical tests
  • Participate in creating and reviewing SOPs and batch records
  • Support campaign activities across other unit operations as-needed

Skills and Requirements:

  • BS in Chemistry with 1-3 years lab experience, preferably in an industrial setting.
  • Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
  • Experience in record-keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
  • Good communication skill is a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.

If you are having difficulty in applying or if you have any questions, please contact Jackie Cerchio at +(1) 267-846-2026 or

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.