Snr Director, Antibody Drug Conjugate Discovery & Engineering

Highly Competitive
  1. Permanent
  2. Biochemistry
  3. United States
Gaithersburg, USA
Posting date: 02 Aug 2022
46893

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We are seeking a Senior Director, Antibody Drug Conjugate Discovery & Engineering to join an innovative biopharmaceutical company and lead a team responsible for the discovery and development of ADCs and nanomedicines as well as other conjugate modalities.

Main Responsibilities:

  • Lead technology development/protein engineering to improve tissue specific targeting and therapeutic index of ADCs and nanomedicines. These include site-specific conjugation, linker engineering, novel warhead development, antibody design and optimisation, and the utilisation of antibody fragments, protein scaffolds, bispecifics and other formats.
  • Interact and collaborate with leaders and teams across key therapeutic areas on pipeline delivery and new technology development. The initial focus is on Oncology, but will extend to multiple therapeutic areas in the near future.
  • Work closely with Technical Operations Teams to ensure new therapeutic molecules are compatible with CMC requirement.
  • Partner with Business Development to pursue investments that further the BE strategy. Establish a network of external partners from academia and industry to strengthen capabilities and capacity in ADC, radioimmunoconjugates and nanomedicine area.
  • Develop and manage operating budget.
  • Provide growth, career development and carry out performance management for staff.

Minimum Requirements:

  • PhD in a relevant scientific area, such as antibody or protein engineering, protein biochemistry, biotechnology or similar field plus a minimum of 10 years of professional experience in biologics research.
  • Recognised leader in scientific specialty as evidenced by publications, participation in international conference, membership on journal editorial boards, etc.
  • He/she must be an excellent communicator and highly effective in interacting with key internal and external stakeholders.
  • Ability to establish high level strategies for new drug technologies, and ability to apply new technologies to drug discovery.
  • The candidate must be a team player and builder, possess great coaching skills and have great organisational skills.
  • The successful candidate must have a high degree of integrity and professionalism.
  • Knowledge in chemistry and cancer biology is a plus.

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at +1 929 388 1651.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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