Senior Scientist RNA Therapies

Highly Competitive
  1. Permanent
  2. Genetics & Genomics
  3. Sweden
Lund, Sweden
Posting date: 22 Feb 2024
59081

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Proclinical are recruiting for a Senior Scientist RNA Therapies to join a biotech organisation. This role is on a permanent basis.

Responsibilities:

  • You will drive novel research on in vitro and in vivo non-viral direct reprogramming modalities, with particular focus on dendritic cell reprogramming and tumor targeting.
  • Responsible for developing functional and analytical strategies to characterise RNA-based vectors.
  • Review RNA based platform ex-vivo efficiency in human monolayer models in terms of cDC1 reprogramming efficacy.
  • The ideal candidate will design, plan, and implement scientific experiments independently to complete program and company goals within designated timelines.
  • Gather and document primary data to uphold updated records.
  • You will analyse, summarise data in reports and discuss the results to the company's R&D and executive leadership team.
  • Other duties may be assigned.

Key Skills and Requirements:

  • Educated to an advanced degree level in Biomedicine, Cell Biology, Immunology, Cancer Biology or a similar discipline, with demonstrable experience in academic or industrial setting.
  • Familiarity with overall in vitro 2D cell culture practices.
  • Acquaintance within the development and application of tumor biology-related in vitro assays, which involves multi-colour flow cytometry for immune profiling, FACS, T-cell cytotoxicity assays, complex cell-based functional assays, for example: antigen presentation and cancer cell cytotoxicity.
  • Prior involvement in RNA biology and development of RNA-based gene therapy vectors, molecular cloning, vector production, encapsulation in nanoparticles and in vivo delivery would be beneficial.
  • Experience within in vivo/in situ gene therapy and cell reprogramming would be advantageous.

If you are having difficulty in applying or if you have any questions, please contact James Hume at j.hume@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

#Scientific

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