Senior Scientist/Research Investigator, AAV Biology job in Boston, USA

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Last Name*

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Job type: Permanent

Discipline: Senior/Director & VP, Biological Sciences, Molecular Biology

Location: United States

This vacancy has now expired. Please see similar roles below...

Proclinical is working with a gene therapy start-up company, developing treatments for CNS and other areas of high unmet medical need. Our client is in search for a Senior Scientist/Research Investigator of AAV Biology for their Boston, MA location, to work in the laboratory and be responsible for experimental development, execution and data analysis for preclinical research studies supporting cutting edge therapeutic programs and AAV platform discovery research in neurodegenerative diseases, metabolic diseases, occular disorders and oncology areas.

Job Responsibilities:

Develop and execute experimental bench work to build up AAV gene therapy platform
Design and optimize AAV vector genome for candidate screening and lead selection
Design and develop novel AAV capsids to meet clinical gene therapy need for various indications
Collaborate with internal and external collaborators
Performing data analyses and delivering data presentation to the scientific team
Ensuring maintenance of industry-quality records to provide documentation
Contribute to high impact research publications/patent applications and regulatory filings

Skills and Requirements:

PhD (+ 5 years) experience in virology, molecular biology, AAV biology or related discipline
Deep knowledge in AAV biology and AAV gene therapy
Hands-on experience with various molecular biology techniques, including DNA/RNA operations, quantitative PCR, RT-qPCR, ddPCR, expression vector design, NGS, shRNA and miRNA
Hands-on experience in AAV vector genome design, capsid engineering, research-grade AAV production and AAV-related QC analytic assays
Hands-on experience in mammalian cell cultures and cell-based assays for drug research and development
Outstanding problem-solving and troubleshooting skills
Must be self-motivated, detail-oriented, organized
Must be capable of working independently as well as in a collaborative/group environment
Good communication and interpersonal skills
Ability to multi-task in a fast-paced work environment
Strong commitment to accountability with can-do attitude for completion of projects in accordance with team plans and timelines

If you are having difficulty in applying or if you have any questions, please contact Sofia Amark at (+1) 646-367-2764 or s.amark@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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