Senior Scientist, Machine Learning & Protein Engineering

Highly Competitive
  1. Permanent
  2. Immunology
  3. United States
Rockville, USA
Posting date: 27 Jun 2024

Senior Scientist, Machine Learning & Protein Engineering - Permanent - Rockville MD

Proclinical is seeking a dedicated Scientist with a focus on machine learning and protein engineering for a senior position.

Primary Responsibilities:

This role is an exciting opportunity to contribute to the development of new cell therapies at a clinical stage immunotherapy company. The ideal candidate will be a pivotal part of the cross-functional teams, leading machine learning-based protein design initiatives and contributing to the development of lead drug candidates.

Skills & Requirements:

  • PhD in computational biology, biophysics, bioinformatics, computer science or another related field.
  • Proven expertise in AI and deep learning algorithms, frameworks, associated programming languages and systems architecture.
  • The ability to independently design, build and evaluate machine learning models.
  • Expertise in state-of-the-art protein design applications such as Rosetta, AlphaFold2, RoseTTAFold, RFdiffusion, ProteinMPNN, etc.
  • Strong working knowledge of protein developability considerations for therapeutic proteins.
  • Ability to work collaboratively and communicate effectively in interdisciplinary teams.

The Senior Scientist, Machine Learning & Protein Engineering's responsibilities will be:

  • Run and work together on machine learning-based protein design initiatives in the development of new cell therapies.
  • Work as a key member of cross-functional teams to identify and develop lead drug candidates.
  • Lead the design and evaluation of novel proteins and de novo biological systems in support of therapeutic programs.
  • Implement and develop machine learning-based protein design solutions for structure prediction, paratope/epitope analysis, affinity maturation, developability assessment, scaffold optimization, library design, immunogenicity and other protein engineering challenges.

If you are having difficulty in applying or if you have any questions, please contact Alex Bero at

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.