Screening and Assay Development Lead job in South San Francisco, USA

First Name*

Last Name*

Email*

Phone Number*

Country*

Are you an employer or a jobseeker?*

Message

First Name*

Last Name*

Email*

Phone Number*

Country*

Are you an employer or a jobseeker?*

Message

First Name*

Last Name*

Email*

Phone Number*

Country*

Are you an employer or a jobseeker?*

Message

First Name*

Last Name*

Email*

Phone Number*

Country*

Are you an employer or a jobseeker?*

Message

Job type: Permanent

Discipline: Biological Sciences, Medicinal Chemistry, Pharmacology

Location: United States

This vacancy has now expired. Please see similar roles below...

Proclinical is seeking a Screening and Assay Development Lead for a cutting-edge biotechnology company located in South San Francisco, CA.

As the Screening and Assay Development Lead, you will spearhead efforts to develop, optimize, establish, and execute biochemical/molecular assays for screening small molecule modulators of RNA targets.

Must be eligible to work in the US.

Job Responsibilities:

Develop, qualify, and validate novel and standard assays in-house. Ensure reproducibility and consistency of screening results and methods.
Provide scientific leadership and in-depth knowledge for biochemical, molecular, and cell-based assays, and interpretation of results.
Independently, proactively, and effectively troubleshoot assay-related issues.
Hire and mentor new members of the team.

Skills and Requirements:

Bachelor's degree and a minimum of 15 years of experience in the industry or PhD in the life sciences and minimum of 10 years of experience in the industry.
Extensive experience in developing and establishing novel and off-the-shelf biochemical, molecular, and cellular assays (cell lines, primary cells, viability/cytotoxicity, ELISA, Western, qPCR, MSD, microscopy, flow cytometry, etc.).
Proficiency in designing, cloning, and working with plasmid- or mRNA-based reporter systems
Hands-on familiarity with small molecule library screening, including lab automation for medium- and high-throughput formats (96- and 384-well plates).
Demonstrated experience with multiple nucleic acid delivery system platforms (electroporation, transfection, viral and non-viral delivery systems).
Substantial experience in managing and mentoring teams.
Ability to plan and execute in a fast-paced environment and agility to adapt to changing priorities.
Excellent presentation and writing skills, ability to clearly communicate technical information to colleagues.
Experience screening small molecule modulators of RNA targets.
Deep understanding of mechanisms and pathways regulating mRNA processing in mammalian cells.
Experience managing and working with CROs to increase screening throughput and deliver results efficiently and cost-effectively.

If you are having difficulty in applying or if you have any questions, please contact Danielle Bahnasy at +(1) 646-868-5142 or d.bahnasy@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

#LI-DB3

INDSCIC

Salary

Highly Competitive

Location:

Basel, Switzerland

Proclinical is currently working alongside a pharmaceutical company seeking a dedicated Parenteral Formulation & Process Development Scientist to join the team.