Scientist in Neuroimmunology job in Basel, Switzerland

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Job type: Contract

Discipline: Immunology

Location: Switzerland

This vacancy has now expired. Please see similar roles below...

Proclinical are recruiting a Scientist in Neuroimmunology for a biotech corporation. This role is on a contract basis. This client is focused on supplying life-changing treatments for major illnesses.

Responsibilities:

Inspect, develop, and instrument new cell functional assays using human iPSC-derived/primary microglia as well as rodent microglia to test and compare efficacy of small molecules.
Leverage a combination of biochemical approaches to investigate cellular pharmacology.
Develop, implement, and study ex vivo slice assays and in vivo models to measure the target biology and test compounds.
You will establish SOPs, acclimate new protocols from literature and maintain electronic laboratory notebooks.
Develop, apply, and examine transcriptomic and proteomic readouts from cells and pre-clinical models to characterise small molecule compounds.
Operate efficiently with internal collaborators across the company to advance the project.
Exhibit data to the project team and at section and departmental meetings.

Skills & Requirements:

Attained a MSc or PhD in (neuro)-immunology, cell/molecular biology or biochemistry.
Proficiency functioning with primary rodent glial cultures, as well as iPSC derived model systems.
Skilled in developing strong and reproducible cell functional assays.
Wide-ranging applied experience with several gene expression, immunoassay, and molecular profiling methods applied to cells and brain tissues (human and rodents).
Capable of independently designing, implementing, and assessing experiments.
Qualification for performing in vivo animal experiments (eg. LTK1) is necessitated. Know-how in in vivo animal dosing, perfusion, tissue collection and preparation for biochemical and immunoassays is an advantage for this role, however, it is not vital.
Exceptional computer-based data management and record-keeping skills; experience with basic biostatistical data analysis is a benefit, but not essential to the role.
Brilliant communication skills to report your results to the team; fluent in writing and speaking in the English language is crucial to the role.
Must enjoy a self-governing operating style and troubleshooting in a multi-departmental and international pharma research atmosphere.
Preceding experience in drug discovery R&D in neuroscience is an advantage, but not critical to the role.
Former experience in cellular pharmacology is a benefit, but not essential to the role.

If you are having difficulty in applying or if you have any questions, please contact Mohammed Alli at +41 61 568 79 85.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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