Research Specialist C

Research Specialist C - Contract - Philadelphia, PA

Proclinical is seeking a Research Specialist C to perform in a supportive independent manner, in vivo mouse studies and colony maintenance which will be carried out for the SWAT Team.

Primary Responsibilities:

The purpose of this position is to establish mouse studies by generating and characterizing engineered immune therapeutics and growing/developing tumor cells, their injections, monitoring animal health/weight and therapeutic responses during these studies by collecting datasets from the study (tumor growth, therapeutic engraftment, histology, ex vivo assays) and involvement in their evaluations and presentation of results. The specialist will also carry out wet lab aspects of spatial transcriptomic studies involving 10x and NanoString platforms by preparing and processing murine and/or human tissue samples for high-resolution profiling.

Skills & Requirements:

• Bachelor's Degree with 3-5 years of laboratory experience in mouse models is required.
• Experience in Immunology and Molecular Technology, is desired.
• Knowledge/understanding in spatial transcriptomics and bioinformatics is a plus.
• Ideal candidate will be an enthusiastic individual wanting to be involved, with a curious and analytical mind desiring to make an impact.

The Research Specialist's responsibilities will be:

• Modify and prepare tumour cells and engineered immune therapies for in vivo mouse experiments, documenting their characteristics and performing assays defining functional performance.
• Monitoring and collecting datasets associated with animal studies, e.g., health monitoring and weights, tumour growth (calliper, bioimaging), bleeds and necropsies.
• Performing IV, IT, SC injections of tumour and therapeutics.
• Tissue preparation at necropsy by fixing and cell isolation for function and flow cytometric analysis, IHC, and spatial transcriptomic studies
• Documentation, data analysis and preparing presentations.
• Other duties and responsibilities as assigned

If you are having difficulty in applying or if you have any questions, please contact Natalie Magola at n.magola@proclinical.com

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

INDCR