Genomics Research Associate - Contract - San Diego, CA
Drive cutting‑edge multi‑omics discovery by leading high‑complexity genomic workflows from tissue to data.
Proclinical is seeking a Genomics Research Associate for a contract role in San Diego, CA.
Primary Responsibilities:
The successful candidate will part of this hands-on role is to drive technical execution for high-complexity genomic data collection projects. You will work largely independently to optimize nuclei extraction protocols across diverse biological variables and execute sophisticated multi-omics workflows.
Skills & Requirements:
- The ideal candidate will have 4+ years of relevant experience, demonstrating a strong track record of independent troubleshooting in a molecular biology/genomics context.
- BS or MS in Molecular Biology, Genetics, Biochemistry, or a related discipline.
- It is essential to have deep practical experience with nuclei isolation and extraction from frozen tissues
- It is essential to have demonstrated experience executing single-cell or single-nuclei sequencing workflows (e.g., 10x Genomics Multiome).
- Ability to work independently, design optimization experiments, and interpret quality control data (e.g., Bioanalyzer/TapeStation traces) without oversight.
- High level of computer literacy to maintain detailed electronic lab notebooks (ELN) and sample records.
- Highly organized and self-motivated, with the ability to manage complex workflows involving sensitive reagents and strict timelines.
- Meticulous attention to detail with a solution-driven mindset, particularly regarding protocol troubleshooting
The Genomics Research Associate's responsibilities will be:
- Lead optimization efforts for nuclei extraction across a complex matrix of tissue types, including multi-species, disease-state, and variable-age samples.
- Independently execute and troubleshoot advanced genomic protocols, including novel genomics protocols, Multiome, and MINT-ChIP.
- Be responsible for the end-to-end processing of samples, from frozen tissue handling to library preparation, ensuring high-quality inputs for sequencing.
- Systematically track optimization metrics to establish robust standard operating procedures (SOPs) for challenging tissue types.
- Lead efforts to implement and maintain inventory and sample tracking systems for high-value genomic libraries.
- Work closely with computational and wet-lab colleagues to plan large-scale data collection and ensure experimental designs meet analytical requirements.
- Set up and operate laboratory equipment (e.g., cell counters, thermocyclers, microfluidics platforms), prepare reagents, record and consolidate research data, and execute planned research activities with minimal supervision.
- Compensation:
$45.00 - $55.00 Per Hour
If you are having difficulty in applying or if you have any questions, please contact Shannon Briggs at s.briggs@proclinical.com
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
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