Director, Oncology DMPK

Director of DMPK - Permanent - Onsite

Proclinical is seeking a Director of DMPK (Oncology) who is passionate about ADME and DMPK science, applied to Cancer biology. This is a permanent role located in Boston, MA.

Primary Responsibilities

The successful candidate will be responsible for supervising ADME scientists and providing drug discovery and development support for a diverse portfolio. This role offers the opportunity to contribute to drug discovery and development across the global Oncology portfolio.

Skills & Requirements:

• PhD or equivalent degree in Pharmaceutical Sciences, Molecular Biology, Chemistry, Biochemistry or Pharmacology with experience in drug discovery, or a higher degree in a research area relevant to DMPK science.
• At least 8+ years of relevant industry experience in ADME/Project Representation or a MS degree with at least 13+ years of relevant industry experience.
• Strong technical knowledge of DMPK science with a proven ability to delineate the impact of chemical structure on measured properties.
• Practical experience of DMPK assay delivery including experimentation, assessment of assay quality and troubleshooting of data issues.
• Track record of successful problem solving, high quality science and influencing of stakeholders, particularly in a drug project context.
• Excellent interpersonal skills that lead to successful collaborative working relationships.
• Good understanding of the drug discovery process and how DMPK studies contribute to that process.
• Desire to carry out scientific development and research work with a view to publishing collaboratively.
• Can-do attitude and a desire to learn and adapt is essential.
• Experience and knowledge of working with multiple modalities including; small molecules, biologics, nano-medicines and PROTACs is a plus.

The Director of DMPK will:

• Supervise and manage a team of ADME scientists, providing expert advice and context for the interpretation of complex data.
• Develop and implement state-of-the-art technologies in the field of drug metabolism and transporters.
• Lead DMPK-related compound design activities to ensure project ADME challenges are thoroughly assessed and resolved.
• Apply expert understanding of DMPK, physico-chemical property assays and/or biotransformation reactions to discovery project chemistry and data.
• Initiate, lead and champion new innovations from external, global and local DMPK project science strategies.
• Carry out collaborative research aligned to DMPK and Oncology objectives and publish research papers and reviews in internationally recognized journals.
• Support the department's leadership team in both the strategic vision for the department and in the efficient and progressive running of the department.
• Manage student and Post Doc programmes.
• Involvement in external collaborative projects with academic or cross-pharma pre-competitive groups.

Compensation:

$200,000 annually

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 857-362-9542 or m.robinson@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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