Director, Oncology DMPK

Up to US$200000 per annum + Highly Competitive Salary
  1. Permanent
  2. Senior/Director & VP, Biological Sciences, Pharmacology
  3. United States
Boston, USA
Posting date: 25 Mar 2024

This vacancy has now expired. Please see similar roles below...

Director of DMPK - Permanent - Onsite

Proclinical is seeking a Director of DMPK (Oncology) who is passionate about ADME and DMPK science, applied to Cancer biology. This is a permanent role located in Boston, MA.

Primary Responsibilities

The successful candidate will be responsible for supervising ADME scientists and providing drug discovery and development support for a diverse portfolio. This role offers the opportunity to contribute to drug discovery and development across the global Oncology portfolio.

Skills & Requirements:

  • PhD or equivalent degree in Pharmaceutical Sciences, Molecular Biology, Chemistry, Biochemistry or Pharmacology with experience in drug discovery, or a higher degree in a research area relevant to DMPK science.
  • At least 8+ years of relevant industry experience in ADME/Project Representation or a MS degree with at least 13+ years of relevant industry experience.
  • Strong technical knowledge of DMPK science with a proven ability to delineate the impact of chemical structure on measured properties.
  • Practical experience of DMPK assay delivery including experimentation, assessment of assay quality and troubleshooting of data issues.
  • Track record of successful problem solving, high quality science and influencing of stakeholders, particularly in a drug project context.
  • Excellent interpersonal skills that lead to successful collaborative working relationships.
  • Good understanding of the drug discovery process and how DMPK studies contribute to that process.
  • Desire to carry out scientific development and research work with a view to publishing collaboratively.
  • Can-do attitude and a desire to learn and adapt is essential.
  • Experience and knowledge of working with multiple modalities including; small molecules, biologics, nano-medicines and PROTACs is a plus.

The Director of DMPK will:

  • Supervise and manage a team of ADME scientists, providing expert advice and context for the interpretation of complex data.
  • Develop and implement state-of-the-art technologies in the field of drug metabolism and transporters.
  • Lead DMPK-related compound design activities to ensure project ADME challenges are thoroughly assessed and resolved.
  • Apply expert understanding of DMPK, physico-chemical property assays and/or biotransformation reactions to discovery project chemistry and data.
  • Initiate, lead and champion new innovations from external, global and local DMPK project science strategies.
  • Carry out collaborative research aligned to DMPK and Oncology objectives and publish research papers and reviews in internationally recognized journals.
  • Support the department's leadership team in both the strategic vision for the department and in the efficient and progressive running of the department.
  • Manage student and Post Doc programmes.
  • Involvement in external collaborative projects with academic or cross-pharma pre-competitive groups.


$200,000 annually

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 857-362-9542 or

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.