Director of Medicinal Chemistry

Proclinical is seeking a Director of Medicinal Chemistry for a leading biotech company located in Boston, MA.

As a senior medicinal chemist reporting to the Head of Chemistry, this person will implement the medicinal chemistry strategy, collaborating with a cross-functional team of scientists and leading a team of external synthetic chemists to progress our drug discovery programs.

Job Responsibilities:

• Co-lead interdisciplinary project teams and work with a team of scientists to progress projects from target selection and validation through candidate selection
• Develop and drive medicinal chemistry lead discovery and optimization strategies
• Prioritize medicinal chemistry activities, manage external chemistry CRO and consulting resources, efficiently managing time and resources
• Build, critically interpret and respond to structure activity relationships incorporating multiple optimization parameters such as pharmacological, DMPK and physicochemical properties
• Apply advanced medicinal chemistry principles to design high quality compounds
• Contribute to the execution of IP strategy in collaboration with intellectual property attorneys
• Clearly and effectively communicate medicinal chemistry strategy and provide progress updates to cross-functional project teams and scientific leadership
• Build and maintain productive relationships with colleagues in chemistry, computational, biomolecular sciences, ADME, biology and pharmacology
• Contribute to developing our innovative drug discovery platform for modulating RNA processing with small molecules
• Contribute to building the chemistry infrastructure and company culture

Skills and Requirements:

• Ph.D. in synthetic organic chemistry or medicinal chemistry with a minimum of 10 years of experience working in a pharmaceutical and/or biotechnology setting as a medicinal chemist
• Demonstrated leadership in medicinal chemistry and drug discovery as evidenced by a strong record of scientific accomplishment utilizing cross functional information
• Outstanding synthetic chemistry knowledge and a demonstrated track record of aptitude and problem solving in medicinal chemistry
• Proven ability to manage timelines and resources to drive projects toward key decision criteria; experience in outsourcing and managing CROs
• Keen attention to detail and a strong sense of urgency is required as is the desire and ability to work in a multi-disciplinary and team-focused environment

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at +(1) 857-362-9542 or m.robinson@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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