Associate Scientist

Proclinical is currently recruiting for an Associate Scientist with a pharmaceutical company located in San Francisco, CA.

Job Responsibilities:

• Provide preclinical Pharmacology support to drug discovery and development projects in oncology.
• Implement novel experimental approaches to tumor model development, efficacy/PK/PD/ in vivo mechanism-of-action investigation, target discovery and validation, disease mechanisms, resistance biology, and tumor microenvironment interaction in support of drug discovery and development.
• Investigate, develop, validate or optimize existing and new methods/models to solve project related scientific problems.
• Generate efficacy and PD data to support preclinical development of drug candidates and regulatory submissions.
• Develop productive collaborations and communications with other groups across scientific disciplines.
• Conduct tumor efficacy, imaging and PD studies to support in vivo POC, SAR and IND submission.
• Report/present analyses of in vivo studies.
• Understand and adhere to IACUC protocols regarding animal welfare and handling.
• Cell culture, sorting and genetic manipulation of cells to support efficacy studies and tumor model development.
• Conduct ex vivo assays such as FACS, MSD, WES and Luminex to understand MOA of in vivo studies.
• Improve existing Pharmacology workflows and data visualization tools.
• Commitment to scientific rigor, high data quality and careful documentation.
• Self-motivated, possess strong problem solving and organizational skills.
• Ability to manage multiple responsibilities, adapt to changing priorities and meet deadlines in a fast-paced environment.
• Excellent written and verbal communication skills.
• Flexibility and motivation to learn techniques and accomplish goals outside those stated above.

Skills and Requirements:

• BS/MS in cancer biology, pharmacology, or related field.
• 0-3 years of hands-on wet lab experience in a pharmaceutical or academic setting.
• Hands-on experience with tissue culture, tumor implantation, tumor measurement and tissue harvesting is preferred
• Technical experience in flow cytometry, primary cell culture, tissue processing, as well as other standard molecular and cellular biology assays (MSD, ELISA, Wes, etc.) is a plus
• Strong teamwork spirit, good listener, eager to learn new skills
• Must be proactive and able to work effectively on multiple experiments in a fast-paced, dynamic environment.
• Strong written and verbal communication skills, good record keeping and organization skills, attention to details
• Demonstrated ability to work independently and collaboratively to execute experiments

If you are having difficulty in applying or if you have any questions, please contact Shanna Sweigart at 570-277-7057. ProClinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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