Associate Scientist job in New York, USA

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First Name*

Last Name*

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Job type: Permanent

Discipline: Biochemistry, Biological Sciences, Immunology

Location: United States

This vacancy has now expired. Please see similar roles below...

Proclinical is working with a dynamic drug discovery team to develop cutting-edge CAR-T therapeutics for the treatment of hematologic malignancies and solid tumors. Our client is in search for an Associate Scientist in their New York, NY location to work in an exciting/stimulating environment across the different stages of preclinical drug discovery (from target ID to FDA/IND filing) on projects related to tumor immunology. The candidate will be strongly motivated and dedicated, will show initiative and work independently.

Job Responsibilities:

Mammalian tissue culture of cell lines and primary human cells and blood products (BSL2 and BSL2+).
Processing and dissociating mouse blood and tumors from in vivo studies for analysis by flow cytometry.
Perform molecular biology techniques such as: transfections, transductions, western blotting, immunoprecipitation, siRNA/shRNA, qRT-PCR, flow cytometry and ELISA (ie. MSD).
Immune functional assays using CAR-T, cytokine release assays, T cell biology, immune cell purification and characterization, tumor dissociation.
Run multiple experiments/projects simultaneously.
Maintain accurate laboratory notebooks and prepare technical reports, summaries, protocols, etc, and maintain familiarity with relevant scientific literature.
Design, perform, interpret, troubleshoot, and report complex data to managers in a clear and concise manner.

Skills and Requirements:

A M.S. with 2-4 years of experience or a B.S. with 4-9 years of experience in Biology, Molecular Biology, Immunology, Cancer Biology or related areas in Life Sciences with related laboratory experience is required.
Aseptic mammalian tissue culture of cell lines and primary human cells (ie. whole blood, PBMCs, and T cells).
Multi-color flow cytometry analysis and interpretation.
Data analysis using common software programs (ie. Excel, GraphPad Prism, and FlowJo).
Related Experience: drug discovery experience in a biotech or pharmaceutical environment.
Previous work with antibody therapies, bispecific antibodies, and cellular therapies (ie. CAR-T).
Functional assays to test drug candidates (ie. cytotoxicity, proliferation, apoptosis).
Immunology and/or oncology experience.
Excellent interpersonal skills with the ability to interact effectively with people, internally and externally.
Excellent oral and written communication skills. Able to effectively present scientific data and concepts to international standards.
Prior experience with isolation, phenotypical and functional characterization of human tumor-infiltrating leukocytes is advantageous.

If you are having difficulty in applying or if you have any questions, please contact Sofia Amark at (+1) 646-367-2764 or s.amark@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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