Associate Scientist, Gene Editing

Highly Competitive Salary
  1. Permanent
  2. Biological Sciences, Genetics & Genomics, Molecular Biology
  3. United States
Cambridge, USA
Posting date: 08 Jan 2021

Proclinical is currently recruiting for an Associate Scientist of Gene Editing for a global biotechnology company located in Cambridge, MA. As the Associate Scientist, you will work closely with the departments of T Cell Immunology, Bioinformatics, Cancer Immunology and Molecular Immunology to develop and assess the efficacy of this approach.

Job Responsibilities:

  • Culturing of primary human T cells and cancer cell lines
  • Genetic manipulation of immune cell cultures
  • Planning and conducting CRISPR/Cas9 screens in vitro
  • Designing and executing cell-based functional assays supporting genetic screens and follow up validation studies
  • Performing molecular biology techniques, including PCR
  • Assessment of specificity and functionality of human T cells by multicolor flow cytometry
  • Tracking and compiling results in an electronic notebook
  • Assisting with the training of lab personnel
  • Interactions with internal collaborators or external CMOs
  • Analyzing and interpreting data, and presenting results to other scientific teams and stakeholders

Skills and Requirements:

  • MS in Immunology or related field with 2-5 years of work experience in immunotherapy or cell therapy.
  • Knowledge and experience with genetic manipulation of primary cells and cell cultures including CRISPR/Cas9 gene-editing tools
  • A strong interest in T cell biology and cancer immunotherapy
  • Primary immune cell culture experience
  • Demonstrated experience with flow cytometry and other immune related assays is required
  • Ability to work independently, as well as in a collaborative environment to meet project goals
  • Excellent attention to detail
  • Excellent written and oral communication skills
  • Enjoys solving challenging scientific questions in a fast pace environment
  • Independent, flexible, self-motivated, and the ability to work well with others

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 617-903-7746 or

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.