Associate Director, Translational Medicine

Proclinical is currently recruiting for an Associate Director of Translational Medicine with a leading biotechnology company located in San Diego, CA. As the Associate Director, you will support key activities associated with translational biology and development of therapeutic antibody programs towards the clinic.

Job Responsibilities:

• Designs and executes translational biology studies supporting preclinical and clinical development of inflammation and immuno-oncology programs.
• Develops guidelines for selection, validation, and prioritization of translational biomarkers, ensuring alignment with product development strategies.
• Works closely with external research collaborators and contractors for preclinical and clinical translational efforts.
• Explores biomarker identification/validation and interface with the discovery and development teams throughout the development process.
• Represents development projects at management meetings as well to external stakeholders.
• Works with Project Management to develop timelines and budgets, and ensure that tasks are completed appropriately - establishing and monitoring measurable research milestones.
• Participates in new target identification, including translational biology assessment of emerging biology within therapeutic areas of strategic interest. Establishes and maintains a network of external experts for molecular and biological target identification and validation
• Fully participates in the planning and preparation of documentation sections required for regulatory filings (e.g. INDs).

Skills and Requirements:

• PhD in the Biological Sciences, with extensive experience in Life Sciences - 10+ years of relevant, direct experience in preclinical clinical development up to Phase 2 clinical studies; or MD with 3-5 years' experience in early clinical development with proven 'translational' expertise (clinician scientist PhD preferred).
• Proven scientific background with preference in the area of inflammation and immunology
• Proven track record in the translational development of drug candidates to include drug treatment approaches, agents in development and the business landscape.
• Ability to effectively design, execute, and troubleshoot experimental protocols to develop new methodologies.
• Current working scientific knowledge of cellular and molecular immunology with a basic understanding of antibodies
• Extensive knowledge of mammalian cell culture, including standard cell biology techniques and, working knowledge of cellular signaling and ELISA assays
• Current knowledge of the design and implementation of multi-color flow cytometry-based screening experiments
• Familiarity with preclinical models of inflammation and autoimmune disease
• Familiarity with database searches
• Experience in developing fit-for purpose biomarker/bioanalytical assays
• Experience in development of quantitative analytical bioassays from complex matrices

If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 617-903-7746 or m.robinson@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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