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Senior Scientist, Vaccines Biomarkers & Assays
- Permanent
- Biological Sciences, Immunology, Molecular Biology
- United States
This vacancy has now expired. Please see similar roles below...
Proclinical is seeking a Senior Scientist of Vaccines, Biomarkers and Assays for a leading clinical stage biotech located in Cambridge, MA. The candidate will be part of teams responsible for advancing therapeutic and vaccine candidates from early discovery to clinical studies. The candidate will design and execute assays to evaluate novel vaccines and antibody-based therapies for viral and bacterial diseases.
Job Responsibilities:
- Develop immunological assays to support the vaccine development pipeline using diverse assay platforms such as MSD, Luminex, and Octet
- Develop and support the routine performance of a variety of ligand binding assays, cell-based assays, neutralization assays as well as flow cytometry panels
- Work closely with CROs to develop assays and immunological endpoint evaluations for supporting CMC product and process development.
- Lead technical transfer of immunological assays to CROs and support life-cycle management of these outsourced assays
- Work closely with cross-functional teams, collaborators and CROs to progress candidates from Discovery through IND-enabling studies
- Develop and implement a variety of functional assays to support the biological characterization of clinical and preclinical vaccine candidates
- Support the evaluation of novel vaccine and therapeutic candidates in vitro and in vivo and ex vivo
- Assist in the identification and validation of new targets for vaccine intervention
- Identify and implement relevant novel immunological approaches and technology to accelerate infectious disease research
- Manage multiple experiments, projects, and interactions with supporting functions simultaneously
- Interpret, troubleshoot, and report complex data
- Propose novel vaccine and therapeutic targets aligned with the infectious disease strategy
Skills and Requirements:
- Ph.D. in Biology, Microbiology, Immunology, or Chemistry with at least 3 years of related postdoctoral research experience.
- Knowledge and experience in CMC process development for vaccines and therapeutics.
- Experience in CRO management and academic collaborations
- Deep understanding of Infectious disease pathogenesis and immunology
- Expertise in the design and set up of a variety of serological assays, cell-based assays, and functional assays.
- Demonstrated ability to design and execute new experimental approaches
- Excellent team spirit, communication, and presentation skills
- Contributions to high impact publications and presentations in the field of bacterial immunology and/or vaccinology.
- Candidate will be curious in exploring new path for evaluating vaccine mediated responses, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes
- Preferred: Expertise in supporting preclinical and clinical vaccine candidates.
- Preferred: 3 years of independent research experience in the pharmaceutical or biotech industry
If you are having difficulty in applying or if you have any questions, please contact Max Robinson at (+1) 857-362-9542 or m.robinson@proclinical.com.
Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.
Proclinical Staffing is an equal opportunity employer.
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