Scientist, Pharmacometrics

Proclinical, in support of our client, are seeking an individual to fill the role of Senior Scientist, Clinical Pharmacology and Pharmacometrics, based in Cambridge, MA. The successful candidate will join a valued pharma team to implement pharmacometric approaches in program decisions.

Responsibilities

• Scope program questions and developing modeling and simulation strategy for clinical programs.
• Analyze and report population pharmacokinetic/pharmacodynamic, exposure-response, and disease progression models.
• Apply simulation methods to support dose selection, trial design, and Go/No-Go decisions.
• Partner with clinical, biostatistics, DMPK, health economics, and regulatory departments.
• Participate in the preparation of reports/abstracts/manuscripts for publications and regulatory documents.

Skills And Qualifications

• PharmD or PhD in pharmaceutics, pharmacokinetics, pharmacometrics, biostatistics, engineering disciples or related field and 2-5 years of post-doctoral experience.
• Strong proficiency in R programming, and in non-linear mixed effects modeling software.
• Good understanding of pharmacokinetic/pharmacodynamic principles and drug development.
• Experience with programming clinical data sets.
• Strong written, verbal, and interpersonal communication skills.
• Strong statistical understanding of hierarchical modeling of longitudinal continuous and non-continuous data.
• Understanding of application of Bayesian methods.
• Application and development of system pharmacology models.

To Apply:

Please click on the Apply button. Please include a short note outlining why you are interested in the role and why you think you are suitable.

In case you have difficulty in applying or if you have any questions, please call Andrew Shen at (+1) 646-367-1089 or upload your resume on our website - www.Proclinical.com.

A full job description is available on request.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

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